FIG. 3.
Macroscopic β-galactosidase expression in brains from Lmo3 mutant mice. (Lmo1+/−; Lmo3Z/+) mice were interbred with (Lmo1+/−; Lmo3Z/Z) mice, and offspring were sacrificed at E19. The brains were dissected and whole mount stained with X-Gal to reveal β-galactosidase expression. Simultaneously, the genotypes of the mice were established using filter hybridization. The whole mount photographs show comparisons of the indicated genotypes of Lmo3 heterozygous (A) and homozygous (B) mouse brains. Abbreviations: ob, olfactory bulb; cc, cerebral cortex; th, thalamus; mb, midbrain; bs, brain stem; sc, spinal cord.