TABLE 4.
Genotypes of litters from intercrosses of Lmo4 heterozygous micea
| Age | No. of pups | No. (%) of pups with genotype
|
||
|---|---|---|---|---|
| Wild type (+/+) | Heterozygous (+/−) | Homozygous (−/−) | ||
| E9.5 | 28 | 9 (32) | 13 (46) | 6 (22) |
| E10.5 | 16 | 3 (19) | 11 (69) | 2 (12) |
| E15.5 | 19 | 5 (26) | 11 (58) | 3 (16) |
| E16.5 | 13 | 3 (33) | 9 (69) | 1 (7) |
| E17.5 | 22 | 5 (23) | 14 (64) | 3 (13) |
| E18.5 | 10 | 4 (40) | 4 (40) | 2 (20) |
| P28 | 151 | 40 (26) | 111 (74) | 0 (0) |
a
Heterozygous Lmo4 null mutant mice (neo insertion) were bred, and the genotypes of embryos or pups were determined by filter hybridization of yolk sac or tail DNA from the indicated number of progeny at embryonic stages E9.5 to E10.5 and E15.5 to E18.5 and at P28.