Table 4.
Cox model for disease-free survival (DFS) and overall survival (OS) statistics of the molecular biologic markers
| Marker | p-value from Wald test for DFS HR (95% CI) * |
|
|---|---|---|
| single marker | multiple markers (Model 5) | |
| bcl-2 (positive vs. negative) |
(Model 1) | |
| 0.4812 | 0.3382 | |
| 0.81 (0.45, 1.46) | 0.79 (0.51, 1.24) | |
| p53 (positive vs. negative) |
(Model 2) | |
| 0.0385 | 0.0029 | |
| 1.56 (1.02, 2.37) | 1.95 (1.26, 3.02) | |
| Blood group antigen A (presence vs. absence) |
(Model 3) | |
| 0.6111 | 0.7463 | |
| 0.88 (0.55, 1.43) | 0.92 (0.55, 1.54) | |
| Mucin (positive vs. negative) |
(Model 4) | |
| 0.0021 | 0.0018 | |
| 1.88 (1.26, 2.81) | 2.05 (1.31, 3.21) | |
| p-value from Wald test for OS HR (95% CI) * |
||
| Marker | single marker | multiple markers (Model 5) |
| bcl-2 (positive vs. negative) |
(Model 1) | |
| 0.1017 | 0.1022 | |
| 0.57 (0.29, 1.12) | 0.54 (0.26, 1.13) | |
| p53 (positive vs. negative) |
(Model 2) | |
| 0.0190 | 0.0005 | |
| 1.71 (1.09, 2.67) | 2.30 (1.44, 3.68) | |
| Blood group antigen A (presence vs. absence) |
(Model 3) | |
| 0.9199 | 0.7981 | |
| 0.98 (0.59, 1.61) | 0.93 (0.55, 1.60) | |
| Mucin (positive vs. negative) |
(Model 4) | |
| 0.0040 | 0.0037 | |
| 1.88 (1.22, 2.89) | 2.03 (1.26, 3.26) | |
*
Hazard ratio and its 95% confidence interval.