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. Author manuscript; available in PMC: 2013 Jun 15.
Published in final edited form as: Cancer Res. 2012 Apr 13;72(12):2970–2979. doi: 10.1158/0008-5472.CAN-11-3396

Figure 7. Coculture with Lymphocytes protects HCT116 and 786-0 against subsequent Gamma Irradiation.

Figure 7

HCT116, 786-0 and Panc2.03 cells were cultured with human PBLs for 24h. Following the culture, the lymphocytes were rinsed off, and the cells were harvested and exposed to gamma irradiation. A, Remaining cell numbers, displayed as a fraction of the control (no gamma irradiation) for cultures previously exposed to 16:1 E:T ratio of PBL (black) and 50:1 E:T ratio of PBL, or no PBLs (red), all with 6000 IU/ml IL-2, are plotted as the mean+/−SD of well replicates (** p < 0.01, ** p < 0.05). B, Number of cytoplasmic LC3 puncta are plotted (mean+/− SD of well replicates), indicative of sustained autophagy at 24h post irradiation.