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IL-17 and IL-22 induce pro-inflammatory cytokine production in HaCaT cells. HaCaT cells were cultured under 100 ng/ml of IL-17 or IL-22 for 48 hours, with or without preincubation of PS1145, at a concentration of 10µM for an hour and collected culture supernatant for ELISA. The data are expressed as the means±standard error of the mean at three independent experiments. NS: not significant. *p<0.05.
