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PrPSc deposition patterns of UK‐1 and UK‐2 following transmission to RIII mice. Representative photographs of PrPSc deposition in the hippocampus and cerebellum are shown for bovine spongiform encephalopathy (BSE) (A). UK‐1 gave two distinct patterns termed UK‐1 (1) (B) and UK‐1 (2) (C). Representative PrPSc IHC labeling for UK‐2 is shown in (D). Scale bars represent 100 µm.
