Figure 8.

PrP^Sc deposition patterns of UK‐1 following transmission to tg338 mice. PrP^Sc labeling in tg338 mice showed distinct patterns and deposition types. The characteristic deposition type and labeling within the habenular bodies are also shown. P₃₃₈ (A) was predominantly punctuate and intraneuronal labeling. G₃₃₈ (B) was characterized by granular labeling within the neuropil and distinctive aggregates within the medial habenular bodies. A number of mice showed a mixture of P₃₃₈ and G₃₃₈ (composite) (C). Scales bars represent 100 µm.