Effects of GPI-1046 at 10 mg/kg (GPI-10, n=6), GPI-1046 at 20 mg/kg (GPI-20, n=6), vehicle (ethanol naïve) (n=6), water naive (water) (n=6) groups on GLT1 expression in PFC. (A) Each panel presents immunoblots for β-tubulin, which was used as a control loading protein, and GLT1. (B) Quantitative analysis revealed a significant increase in the ratio of GLT1/β-tubulin in the GPI-10 and GPI-20 groups as compared to the vehicle (ethanol naïve) group. In addition, a significant increase in GLT1 expression was revealed in GPI-20 group as compared to naive group. Error bars indicate SEM. (*p<0.05; **p<0.01.)