Table 2.

Population frequency of rare allele of selected SOD2 SNPs

Gene	Chr	SNP	chr loc	Signif.	A1	A2	CaucA. C n=290 f(A1)	CauA Pat. n=458 F(A1)	MexA C n=184 f(A1)	MexA Pat n=672 f(A1)
SOD2	6	rs5746136	160023074	int5	A	G	0.30	0.31	0.26	0.28
SOD2	6	rs2758331	160025060	int4	A	C	0.45	0.50	0.58	0.52
SOD2	6	rs5746129	160025933	p.W156R	T	C	0.004	0.00	0.01	0.00
SOD2	6	rs2855116	160026115	int3	G	T	0.46	0.48	0.55	0.53
SOD2	6	rs2070994	160029041	int3	A	T	0.45	0.50	0.57	0.54
SOD2	6	rs2758339	160032574	int2	C	A	0.53	0.50	0.42	0.43
SOD2	6	rs5746105	160032628	int2	C	T	0.31	0.31	0.28	0.28
SOD2	6	rs4987023	160033683	p.R76G	A	G	0.00	0.00	0.02	0.00
SOD2	6	rs5746097	160033712	p.V66E	T	A	0.01	0.00	0.00	0.00
SOD2	6	rs1799725	160033862	p.A16V	T	C	0.18	0.14	0.10	0.11

Notes: Chr – chromosome number, loc – location, signif – significance of SNP by function or location with respect to gene loci, int-intron, A1 – rare allele, A2 – common allele, CauA – Caucasian American, MexA – Mexican American, Pat – patient with MM, C- SNP control population, n=number of chromosomes tested, f(A1) – frequency of rare allele