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. Author manuscript; available in PMC: 2012 Nov 26.
Published in final edited form as: Vaccine. 2008 Aug 14;26(42):5407–5415. doi: 10.1016/j.vaccine.2008.07.081

Fig. 2.

Fig. 2

Exercise had no effect on APC function but enhanced CD4+ T cell proliferation assessed via mixed lymphocyte response. (a) BALB/c CD4+ T cell proliferation induced by increasing concentrations of allogeneic APC from AL (●) or AL+EX (■) C57BL/6 mice. Data shown are mean ± SEM (n=8/group). Two-way ANOVA revealed no significant effect of exercise on the antigen presenting capability of splenocytes (F2, 70 = 1.89, P = 0.191) (b) C57BL/6 CD4+ T cell proliferation from AL (●) or AL+EX (■) induced by increasing concentrations of allogeneic BALB/c APCs. Data shown are mean ± SEM (n=8/group). Two-way ANOVA revealed a significant effect of exercise on CD4+ T cell proliferation in response to simulation with allogeneic APC (F 1,84 = 8.14, P = 0.006). *Post-hoc analyses using Bonferroni’s test for multiple comparisons found significant differences between AL and AL+EX groups at the designated concentration of APCs.