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VK3 suppresses growth of hepatic cysts in 3-D cultures. Representative images of cystic structures derived from (A) PCK (n=7) and (B) normal rats (n=5). They were treated with VK3 (50 μM) daily for total of 5 days. Magnification, x4 (A) and x10 (B). Graphs show the effects of different doses of VK3 on cyst enlargement assessed by changes in their circumferential areas. * - P<.05.
