Table 1.
Evaluation of implant integrity at each exit site | ||||||
---|---|---|---|---|---|---|
poly(HEMA) | silicone | |||||
Implant duration |
Intact | Broken @ exit site |
Covered with skin |
Intact | Broken @ exit site |
Covered with skin |
14 days | 16/16 | 0 | 0 | 16/16 | 0 | 0 |
1 mo | 16/16 | 0 | 0 | 16/16 | 0 | 0 |
3 mo* | 5/10 | 4/10 | 1/10 | 10/10 | 0 | 0 |
6 mo† | 1/14 | 5/14 | 8/14 | 12/14 | 0 | 2/14 |
Data represents results for 14 day, and 1, 3, and 6 month harvests for 8, 8, 5 and 7 mice, respectively.
Only 5 mice were included for the 3 month harvest because confirming gross images for 3 mice could not be analyzed.
One mouse for the 6 month harvest was euthanized early due to malocclusion of the teeth.