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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Brain Behav Immun. 2012 Jul 24;26(7):1150–1159. doi: 10.1016/j.bbi.2012.07.011

Fig. 3.

Fig. 3

β-adrenergic antagonism treatment of socially defeated mice significantly altered spleen weight but not serum corticosterone. Male CD-1 mice were injected s.c. with vehicle or propranolol prior to defeat each day for 6 days. Corticosterone was measured via radioimmune assay from defeated (SDR; filled bars) and home cage control (HCC; open bars) mice in the serum obtained via retro orbital plexus (A) immediately following the last cycle of SDR (i.e., at 1900 EST) and at 18 h after the last cycle of SDR (i.e. at 0900 EST). (C) Spleen and body weight were measured the day after the last cycle of defeat and a relative spleen mass (spleen mass/body mass) was calculated. Bars represent the mean ± SEM (n = 9). Means with different letters (a or b) are significantly different (p < 0.05) from each other.