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. 2012 Oct 8;55(22):9868–9874. doi: 10.1021/jm301096s

Scheme 1.

Scheme 1

(i) BBr3, CH2Cl2 (50%); (ii) MeO2CCHCHCOCl, Na2CO3, THF, H2O (81%); (iii) H2, Pd/C, MeOH (62%).