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. Author manuscript; available in PMC: 2012 Nov 26.
Published in final edited form as: Psychiatr Clin North Am. 2012 Jun;35(2):495–519. doi: 10.1016/j.psc.2012.03.010

Fig. 6.

Fig. 6

Functional polymorphisms in ethanol metabolism: ADH1B His48Arg and ALDH2 Glu487Lys. Higher activity of ADH1B, conferred by Arg48, or lower activity of ALDH2, conferred by Lys487, leads to accumulation of acetaldehyde after alcohol consumption and the flushing reaction.