Table I.
Viral and Histological Analysis following MCMV Inoculation
| I.p. | I.g. | |||
|---|---|---|---|---|
| VIRUS PREPARATION | MCMV | tcMCMV | MCMV | tcMCMV |
| SG a | ||||
| 4 | +/− | − | + | + |
| 7 | +/− | + | + | ++ |
| 14 | +++ | + | + | + |
| 21 | +++ | + | ++ | ++ |
| SPLEEN b | ||||
| 4 | − | − | − | − |
| 7 | +++ | − | + | − |
| 14 | +++ | + | ++ | + |
| 21 | ++ | + | ++ | + |
| LIVER c | ||||
| 4 | +++ | + | + | − |
| 7 | ++ | ++ | ++ | − |
| 14 | ++ | + | + | + |
| 21 | ++ | + | + | + |
a
salivary gland pathology: + + + (severe, >50 foci), + + (moderate, 10–0 organized foci), + (mild, <10 foci), − (normal).
b
spleen pathology: + + + (severe, necrosis), + + (moderate, some pathology, hyperplasia of white pulp), + (mild, stimulated spleen with secondary follicles), − (normal, unstimulated spleen with primary follicles).
c
liver pathology: + + + (severe hepatitis, <100 foci), + + (moderate hepatitis, 10–00 foci), + (mild hepatitis, <10 foci), − (normal).