Table III.
Frequency of alleles and genotypes of 1858 PTPN22 gene in patients with T1D relating to age at onset
| Allele/genotype PTPN22 1858 | Type 1 diabetes age range 0-5 years (n = 26) | Type 1 diabetes agerange 6-15 years (n = 100) | Type 1 diabetes age range 16-25 years (n = 49) | Value of p for trend |
|---|---|---|---|---|
| C | 45 (86%) | 164 (82.8%) | 63 (71.6%) | 0.017* |
| T | 7 (13.5%) | 34 (17.2%) | 25 (28.4%) | |
| CC | 20 (76.9%) | 72 (72.0%) | 28 (57.1%) | 0.048* |
| CT | 5 (19.2%) | 22 (22.0%) | 17 (34.7%) | |
| TT | 1 (3.9%) | 6 (6.0%) | 4 (8.2%) |
*
Cochran-Armitage trend test