Table IV.
Frequency of HLA DR3/DQB1*02, DR4/DQB1*0302, DQB1*0602 genotypes relating to age at onset of T1D and LADA
| Genotype HLA | Type 1 diabetes age range 0-5 years (n = 26) | Type 1 diabetes age range 6-15 years (n = 100) | Type 1 diabetes age range 16-25 years (n = 49) | LADA > 30 (n = 80) | Value of p for trend |
|---|---|---|---|---|---|
| DR3/DQB1*02 | 18 (69.2%) | 57 (57.0%) | 25 (51.0%) | 37 (46.3%) | 0.032 |
| DR4/DQB1*0302 | 21 (80.8%) | 63 (63.0%) | 25 (51.0%) | 35 (43.8%) | 0.0003 |
| DQB1*0602 | 0 (0.0%) | 1 (1.0%) | 1 (2.0%) | 5 (6.3%) | 0.029 |
*
Cochran-Armitage trend test