Skip to main content
. Author manuscript; available in PMC: 2013 Oct 26.
Published in final edited form as: Cell. 2012 Oct 26;151(3):547–558. doi: 10.1016/j.cell.2012.09.034

Figure 5. Poly I:C accelerates CPP-induced target gene expression.

Figure 5

(A) Relative fold change in gene expression levels of Jarid2 following pMX-Sox2 (red line), CPP-SOX2 (blue line) or poly I:C + CPP-SOX2 (green line) treatments. (B) Summary figure of these selected genes (i.e. Jarid2, Zic2, bMyb, Oct4, Sox2, and Nanog) exhibiting the temporal pattern of average gene expression following each treatment. Poly I:C markedly enhances the expression of downstream genes by CPP-SOX2. (C) Relative fold change in gene expression levels of Nanog following pMX-Oct4, CPP-OCT4 or Poly I:C + CPP-OCT4 treatments. (D) Summary figure of these selected genes (i.e. Tcf4, Gap43, Nanog, Sox2 and Oct4) exhibiting the temporal pattern of gene expression following each treatment. Poly I:C markedly enhances the expression of downstream genes by CPP-Oct4. All data represented as mean ± s.d., n=3, *P <0.005.