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. 2012 Oct 24;12:94. doi: 10.1186/1471-2261-12-94

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Copyright ©2012 Iqbal et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Photomicrograph of rat spleen treated with betel nut at two different doses. (1A) Section of spleen from a rat treated with 60 mg/day dose of betel nut for 5 weeks. Numerous foci of extramedullary erythropoiesis with megakaryocytes (marked by arrow). H & E, Mag: 20X. (1B) Photomicrograph IA at a higher magnification (Mag: 40X). (1C) Section of spleen from a rat treated with 30 mg/day dose of betel nut for 5 weeks. Few foci of extrameduallary hematopoiesis; megakaryote marked by arrow. H & E, Mag: 20X. (1D) Section of a spleen from an age-matched control rat treated with water. No extramedullary hematopoiesis is seen. H & E, Mag: 20X.