Table 1.
Clinical and biological data at admission in the intensive care unit
| Characteristics |
SIRS |
Sepsis |
||
|---|---|---|---|---|
| n = 20 | Total n = 40 | Survivors n = 20 | Non-survivors n = 20 | |
|
Age (years) |
55.4 ± 21.4 |
56.2 ± 19.8 |
52.7 ± 21.5 |
59.8 ± 17.8 |
|
Gender (n, %) |
|
|
|
|
| Male |
7 (35) |
28 (70) |
16 (80) |
8 (40) |
| Female |
13 (65) |
12 (30)* |
4 (20) |
12 (60) |
|
temperature (°C) |
37.31 ± 0.6 |
37.70 ± 1.1 |
37.97 ± 0.9 |
37.43 ± 1.1 |
|
WBC counts (×10∧9/L) |
11.7 (9.3-13.0) |
10.5 (7.7-17.0) |
10.1 (7.7-12.6) |
12.6 (7.4-21.9) |
|
serum CRP (mg/dl) |
3.4 (1.7-6.0) |
11.6 (4.3-17.1)* |
8.4 (3.1-15.5) |
13.1 (6.1-18.2) |
|
serum PCT (ng/ml) |
0.3 (0.2-1.4) |
1.9 (0.4-7.4) |
1.9 (0.2-7.9) |
2.0 (0.6-7.9) |
|
serum sCD163 (ng/ml) |
0.3 (0.2-0.4) |
2.9 (1.6-11.3)* |
1.7 (1.1-4.5) |
10.2 (2.7-18.2)# |
|
Renal characteristics |
|
|
|
|
| Urinary output (ml/Kg/hr) |
- |
1.5 (1.1-1.9) |
1.5 (1.0-1.9) |
1.5 (1.1-2.1) |
| CCr(ml/min) |
- |
90.1 (38.5-120.3) |
94.3 (65.7-141.5) |
53.1 (31.2-107.0) |
| SCr(μmmol/L) |
- |
68.0 (55.8-130.7) |
63.1 (53.6-96.6) |
79.5 (62.1-110.1) |
| BUN(mmol/L) |
- |
9.2 (6.5-15.6) |
7.7 (5.9-10.3) |
11.5 (8.9-29.9)# |
|
APACHEII score |
11.8 ± 6.7 |
16.6 ± 7.3* |
12.3 ± 6.4 |
20.9 ± 5.5# |
|
SOFA score |
- |
7.9 ± 4.0 |
6.1 ± 2.9 |
9.6 ± 4.2# |
|
MV (n, %) |
13 (65) |
31 (77.5) |
14 (70) |
17 (85) |
|
CRRT (n, %) |
1 (5) |
12 (30)* |
4 (20) |
8 (40) |
|
Etiological factors (n, %) |
|
|
|
|
| Pulmonary infection |
- |
35 (87.5) |
18 (90) |
17 (85) |
| Abdominal infection |
- |
9 (22.5) |
6 (30) |
3 (15) |
| Urinary tract infection |
- |
11 (27.5) |
8 (40) |
3 (15) |
| Trauma/postoperative infection |
- |
16 (40) |
10 (50) |
6 (30) |
| Bacteremia |
- |
13 (32.5) |
8 (40) |
5 (25) |
| Catheter-related infections |
- |
8 (20) |
5 (25) |
3 (15) |
| Others |
- |
1 (2.5) |
1 (5) |
0 (0) |
|
Pathogens (n, %) |
|
|
|
|
| Gram-positive bacteria |
- |
|
11 (55) |
8 (40) |
| Gram-negative bacteria |
- |
|
18 (90) |
15 (75) |
| Fungi |
- |
|
11 (55) |
11 (55) |
|
underlying diseases (n, %) |
|
|
|
|
| Hypertension |
6 (30) |
12 (30) |
6 (30) |
6 (30) |
| Diabetes |
2 (10) |
7 (17.5) |
3 (15) |
4 (20) |
| COPD |
0 (0) |
3 (7.5) |
3 (15) |
0 (0) |
| Coronary heart disease |
3 (15) |
4 (10) |
2 (10) |
2 (10) |
| Immunosuppressed |
0 (0) |
7 17.5) |
2 (10) |
5 (25) |
| Nervous system disease |
0 (0) |
3 (7.5) |
2 (10) |
1 (5) |
| CKD | 1 (5) | 7 (17.5) | 3 (15) | 2 (10) |
Quantitative data of normal distribution are presented as mean ± SD. Quantitative data of non-normal distribution are presented as median (25th and 75th percentiles). Qualitative data are presented as n (%).
APACHE score, Acute Physiologic Assessment and Chronic Health Evaluation II scores; SOFA score, Sequential Organ Failure Assessment scores; MV, mechanical ventilation; CRRT, continuous renal replacement therapy; COPD, chronic obstructive pulmonary disease; CKD, chronic kidney disease.