Table III.
Differentially expressed miRNAs detected in various conditions.
| Expression change | Total detected | Detected miRNAs |
|---|---|---|
| Normal↑ | 8 | miR-18b*, miR-296-5p, miR-557, miR-581, miR-625*, miR-1228, miR-1249, miR-2116* |
| Tumor↑ | 1 | miR-183 |
| Tumor↓ | 5 | miR-29c, miR-129*, miR-146b-3p, miR-448, miR-486-5p |
| HCV infection↑ | 125 | let-7a, let-7c, miR-22, miR-23a, miR-93, miR-100, miR-106b, miR-126, miR-135a, miR-210 |
| HCV infection↓ | 7 | miR-143, miR-548q, miR-670, miR-711, miR-718, miR-759, miR-762 |
| HCC-C↑ | 68 | miR-31, miR-96, miR-103-2*, miR-130b*, miR-132, miR-134, miR-138, miR-184, miR-301a, miR-372 |
| HCC-C↑, V(-)_T↓ | 24 | let-7a2, miR-21*, miR-25*, miR-33a*, miR-92b*, miR-127-3p, miR-149, miR-330-5p, miR-338-3p, miR-517* |
| HCV↑ | 94 | miR-10a, miR-101, miR-130a, miR-146a, miR-155, miR-181b, miR-195, miR-197, miR-200a, miR-200b |
| HCV↑, V(-)_N↓ | 10 | miR-30b*, miR-187*, miR-188-5p, miR-193b, miR-199a-5p, miR-542-5p, miR-574-5p, miR-658, miR-720, miR-1287 |
| HCV↓ | 7 | let-7b*, miR-139-3p, miR-220c, miR-616*, miR-708, miR-767-3p, miR-1911 |
| HBV infection↑ | 1 | miR-422a |
| HCC-B↑ | 2 | miR-605, miR-1909 |
| V(-)↑ | 1 | miR-217 |
| V(-)↓ | 5 | miR-92a-2*, miR-361-3p, miR-513a-5p, miR-1234, miR-1914* |
| V(-)_T↑ | 1 | miR-216a |
| V(-)_T↓ | 10 | miR-133a, miR-199b-5p, miR-338-5p, miR-491-3p, miR-509-3-5p, miR-543, miR-627, miR-887, miR-921, miR-1247 |
| V(-)_N↓ | 6 | miR-664, miR-671-3p, miR-1246, miR-1268, miR-1280, miR-1978 |
Normal↑ denotes downregulation in the tumor and non-tumor tissues when compared with normal liver. Tumor↑ denotes upregulation in the tumor tissues only and no alteration in the non-tumor tissues. HCV infection↑ denotes upregulation in the tumor and non-tumor tissues in patients with HCV infection while HCV↑ denotes upregulation in the non-tumor tissue of such patients. V(-) denotes patients without virus infection. HCC, hepatocellular carcinoma; HBV, hepatitis B virus; HCV, hepatitis C virus. The double-underlined miRNAs have been previously reported to be involved in HCC while the miRNAs with a single underline have a reported association with other types of cancer.