. Author manuscript; available in PMC: 2012 Nov 26.

Published in final edited form as: J Proteome Res. 2011 Jan 7;10(1):191–199. doi: 10.1021/pr1011137

Table 1.

Comparison of Differentially Regulated miRs with the Counter Regulated Proteins Identified

miRs				target proteins
name	reference	DNA locus	RCC related region	name	reference
Down-regulated miRNA
miR-21^a	56	17q23	17q21 loss of het.¹⁰¹	Retinal dehydrogenase 1	78, 79, 82, 84
miR-21^a				Phosphoglucomutase-1	69
miR-30a	26, 58, 59	6q13	loss 6q^66,103	Dihydropyrimidinase-related protein 2	77, 84
miR-133b	58, 59	6p12	loss 6p⁶⁵	Ferritin light chain	86
miR-133b				N-myc downstream-regulated gene 1 protein	84
miR-138	35, 59	3p21	loss of 3p,^65,103 loss of 3p21-pter⁶⁶	3′(2′),5′-bisphosphate nucleotidase 1	83
miR-141	26, 35, 56, 58–60	12p13		Glutaminase kidney isoform	77
miR-141				Nucleoside diphosphate kinase A	86
miR-200a	56, 58, 59	1p36	loss 1p¹⁰²	Aspartyl-tRNA synthetase	84
miR-200a				Nucleoside diphosphate kinase A	86
miR-200b	26, 57–60	1p36	loss 1p¹⁰²	Chloride intracellular channel protein 4	69
				Fibronectin	82
				Stress-70 protein	79
				Moesin	77
miR-200c	26, 35, 56–60	12p13		Chloride intracellular channel protein 4	69
				Stress-70 protein	79
				Moesin	77
miR-204	26, 56, 58, 59	9q21	loss 9⁶⁶	Ezrin	82
miR-204				Lamin-A	82
miR-429	26, 56, 58, 59	1p36	loss 1p¹⁰²	Chloride intracellular channel protein 4	69
				Four and a half LIM domains protein 1	82
				Fibronectin	82, 84
				Moesin	77
miR-510	26, 58, 59	Xq27	loss Xq^65,66,102	Peptidyl-prolyl cis-trans isomerase A	78
miR-514	26, 35, 58, 59	Xq27	loss Xq^65,66,102	UDP-glucose 6-dehydrogenase	83
Up-regulated miRNA
miR-21	26, 57–59	17q23	gain 17q⁶⁵
miR-34a	56, 58, 59	1p36	add(1)(p34)¹⁰⁴	Calbindin	81, 85
miR-34b	56, 58, 59	11q23		Calbindin	81, 85
miR-106a	57, 59, 60	Xq26	gain Xq⁶⁵	Guanosine-diphosphatase	85
miR-106a				Sorting nexin-9	69
miR-106b	57–60	7q22	trisomy 7,¹⁰³ gain 7^65,66	6-phosphofructokinase type C	78
miR-106b				Sorting nexin-9	69
miR-155	26, 35, 58–60	21q21	del(21)(q22)¹⁰⁴	4-aminobutyrate aminotransferase	75, 82, 84
miR-155				Glycine amidinotransferase	81, 82, 84, 85
miR-185	26, 58, 59	22q11		ATP synthase subunit beta	83, 84
				Guanosine-diphosphatase	85
				14-3-3 protein gamma	85
miR-224	26, 35, 58, 59	Xq28	gain Xq⁶⁵	Argininosuccinate synthase	75, 81, 84
miR-224				Fibrinogen beta chain	82

miR-21: 6 times detected, only one time a down-regulation; het.: heterozygosity.