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. 2012 Sep 19;4(6):1329–1334. doi: 10.3892/ol.2012.922

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Figure 1. — Cutaneous Merkel cell carcinoma involving inguinal lymph nodes, bone, liver and humerus metastases identified by follow-up PET-CT. (A) Large lymph node metastases observed at initial presentation (large arrow). (B) Following initiation of chemotherapy (EP regimen), lymph node metastases shrunk (large arrow) but metastasis to the vertebra occurred (small arrow). (C) Following chemotherapy (IP regimen) and radiotherapy, lymph node metastases recurred and vertebral metastases shrunk (small arrow). (D) Disappearance of lymph nodes and vertebral metastases following concomitant treatment with chemotherapy (IP regimen) and radiotherapy. (E) Following 4 months of combination therapy, metastases in the liver (large arrow) and humerus (small arrow) were discovered by PET-CT follow-up. EP regimen, etoposide/cisplatin; IP regimen, irinotecan/cisplatin. PET-CT, positron emission tomography-computed tomography.