Table III.
Immunohistochemical results of GLUT-1, PI3K and p-Akt in adenoid cystic carcinomas, inflammatory lesions and benign tumors.
| GLUT-1
|
PI3K
|
p-Akt
|
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Group | N | + | − | P-value | + | − | P-value | + | − | P-value |
| Inflammatory lesions | 30 | 0 | 30 | <0.001 | 0 | 30 | <0.001 | 0 | 30 | <0.001 |
| Benign tumors | 25 | 0 | 25 | <0.001 | 1 | 24 | <0.001 | 3 | 22 | <0.001 |
| ACC | 42 | 16 | 26 | <0.001 | 16 | 26 | 0.001 | 21 | 21 | <0.001 |
There was a significant difference among the 3 groups of adenoid cystic carcinomas, inflammatory lesions and benign tumors. When compared with inflammatory lesions and benign tumors, the expression of GLUT-1, PI3K and p-Akt in ACC was higher (Fisher’s exact test). GLUT-1, glucose transporter 1; PI3K, phosphatidylinositol 3-kinase; p-Akt, phosphorylated protein kinase B.