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. 2012 Sep 5;4(6):1234–1240. doi: 10.3892/ol.2012.895

Table III.

Immunohistochemical results of GLUT-1, PI3K and p-Akt in adenoid cystic carcinomas, inflammatory lesions and benign tumors.

GLUT-1
PI3K
p-Akt
Group N + P-value + P-value + P-value
Inflammatory lesions 30 0 30 <0.001 0 30 <0.001 0 30 <0.001
Benign tumors 25 0 25 <0.001 1 24 <0.001 3 22 <0.001
ACC 42 16 26 <0.001 16 26 0.001 21 21 <0.001

There was a significant difference among the 3 groups of adenoid cystic carcinomas, inflammatory lesions and benign tumors. When compared with inflammatory lesions and benign tumors, the expression of GLUT-1, PI3K and p-Akt in ACC was higher (Fisher’s exact test). GLUT-1, glucose transporter 1; PI3K, phosphatidylinositol 3-kinase; p-Akt, phosphorylated protein kinase B.