Table IV.
Correlation between the clinicopathological features and expression of GLUT-1, PI3K and p-Akt.
| Clinicopathological features | N | GLUT-1 + | χ2 | P-value | p-Akt + | χ2 | P-value | PI3K + | χ2 | P-value |
|---|---|---|---|---|---|---|---|---|---|---|
| Gender | ||||||||||
| Female | 29 | 11 | 0.12 | >0.05 | 15 | 0.20 | >0.05 | 10 | 0.52 | >0.05 |
| Male | 13 | 5 | 6 | 6 | ||||||
| Age (years) | ||||||||||
| <60 | 27 | 9 | 0.73 | >0.05 | 14 | 0.10 | >0.05 | 11 | 0.22 | >0.05 |
| ≥60 | 15 | 7 | 7 | 5 | ||||||
| Histopathological type | ||||||||||
| Cribriform | 28 | 11 | 0.54 | >0.05 | 12 | 2.17 | >0.05 | 10 | 0.32 | >0.05 |
| Tubular | 4 | 2 | 2 | 2 | ||||||
| Solid | 10 | 3 | 7 | 4 | ||||||
| T stage | ||||||||||
| T1 | 14 | 1 | 14.15 | 0.003 | 4 | 4.64 | >0.05 | 4 | 4.84 | >0.05 |
| T2 | 15 | 5 | 8 | 4 | ||||||
| T3 | 9 | 7 | 6 | 5 | ||||||
| T4 | 4 | 3 | 3 | 3 | ||||||
| Lymph node metastasis | ||||||||||
| Yes | 22 | 11 | 2.77 | >0.05 | 10 | 0.38 | >0.05 | 10 | 1.06 | >0.05 |
| No | 20 | 5 | 11 | 6 | ||||||
| Site | ||||||||||
| Major salivary gland | 16 | 6 | 0.27 | >0.05 | 8 | 1.18 | 7 | |||
| Minor salivary gland | 22 | 8 | 10 | 9 | ||||||
| Other | 4 | 2 | 3 | >0.05 | 0 | 2.75 | >0.05 | |||
| Metastasis | ||||||||||
| Yes | 4 | 4 | Fisher’s Exact test | 0.016 | 3 | Fisher’s Exact Test | 0.61 | 2 | 0.27 | >0.05 |
| No | 38 | 12 | 18 | 14 | ||||||
| Recurrence | ||||||||||
| Yes | 17 | 12 | Fisher’s Exact test | 0.001 | 15 | 16.7 | <0.001 | 11 | 8.58 | 0.003 |
| No | 25 | 4 | 6 | 5 |
GLUT-1, glucose transporter 1; PI3K, phosphatidylinositol 3-kinase; p-Akt, phosphorylated protein kinase B.