Table 2. Lung function before and after Symbicort Turbuhaler (160/4.5 μg ×2) inhalation in patients with asthma and COPD (x±s).
| Time (min) | FEV1 (L) | FVC (L) | FEV1/FVC (%) | IC (L) | Predicted FEV1(%) | |
|---|---|---|---|---|---|---|
| Asthma (n=30) | baseline 3 10 30 |
1.46±0.48 1.70±0.53 1.82±0.57 1.82±0.61 |
2.69±0.73 3.02±0.76 3.11±0.82 3.17±0.82 |
54.29±10.70 56.53±11.65 56.69±11.93 57.45±13.28 |
1.96±0.57 2.15±0.65 2.27±0.66 2.37±0.68 |
50.79±15.75 59.48±17.92 63.55±19.99 63.13±19.72 |
| COPD (n=62) | baseline 3 10 30 |
1.16±0.52 1.24±0.46 1.27±0.48 1.28±0.49 |
2.11±0.62 2.39±0.59 2.46±0.58 2.49±0.57 |
50.61±10.57 50.93±12.12 50.57±12.05※ 50.40±12.57※ |
1.70±0.62 1.80±0.54 1.86±0.51 1.86±0.48 |
49.25±18.84 53.27±19.03 54.45±19.34 54.90±19.89 |
| Treatment main effect | F P |
17.84 <0.001 |
19.67 <0.001 |
4.76 0.032 |
10.69 0.002 |
2.31 0.132 |
| Time main effect | F P |
60.46 <0.001 |
117.33 <0.001 |
3.78 0.017 |
18.15 <0.001 |
64.63 <0.001 |
| Treatment × time interaction effect | F P |
16.51 <0.001 |
1.40 0.25 |
4.28 0.01 |
3.11 0.045 |
10.24 <0.001 |
Notes: P values of all comparison of each time point after treatment comparing with baseline in asthma group were <0.05, ※indicates that P values of FEV1/FVC in each time point after treatment comparing with baseline in COPD group were >0.05, others were <0.05.