Table 3. Fatty acid composition in the liver and serum of ob/ob mice.
| Species | Diet | Liver | Serum | |||
|---|---|---|---|---|---|---|
| |
Chow |
KD |
Chow |
KD |
Chow |
KD |
| C14:0 | 0.6 | 2.9 | 0.6 | 0.4 | TR | TR |
| C16:0 | 16.9 | 22.7 | 23.1 | 22.6 | 21.6 | 16.3 |
| C16:1 | 1.3 | 1.5 | 9.5 | 1.1 | 3.8 | 0.4 |
| C18:0 | 2.2 | 11.2 | 2.8 | 8.3 | 11.2 | 15.5 |
| C18:1 | 23.9 | 35.3 | 52.5 | 23.9 | 23.0 | 9.0 |
| C18:2 | 45.2 | 22.5 | 6.8 | 30.6 | 20.7 | 33.4 |
| C18:3 | 2.9 | 0.9 | ND | 0.9 | TR | TR |
| C20:1 | ND | ND | 0.7 | 0.4 | TR | TR |
| C20:3 | ND | ND | 0.4 | 0.8 | 1.0 | 0.6 |
| C20:4 | ND | ND | 1.0 | 4.9 | 6.9 | 14.8 |
| C20:5 | 1.5 | ND | ND | ND | 4.1 | 0.9 |
| C22:5 | ND | ND | 0.2 | 0.5 | 0.5 | 0.9 |
| C22:6 | ND | ND | 0.8 | 3.0 | 3.5 | 2.5 |
| Others | 5.5 | 3.0 | 1.6 | 2.6 | 3.7 | 5.7 |
Abbreviations: Chow, regular chow diet; GLC, gas-liquid chromatography; KD, ketogenic diet; ob, obese.
Fatty acid analysis was conducted by GLC. Data represent ratio of each fatty acid species to total fatty acids (%) prepared from the liver and serum of Chow- or KD-fed ob/ob mice, respectively. The column of Diet indicates fatty acid profiles of Chow (CE-2) and KD (F3666) using this study. Values indicate ND, not detected; TR, trace.