Skip to main content
. 2012 Sep 6;120(22):4285–4291. doi: 10.1182/blood-2012-07-438408

Table 4.

Hematology parameters before and after transplant

Patient ID Donor
Recipient 6 mo post-BMT
Chimerism, 6 mo post-BMT Bilirubin, pre-BMT Bilirubin, 6 mo post-BMT Reticulocytes, pre-BMT Reticulocytes, 6 mo post-BMT Hemoglobin, pre-BMT Hemoglobin, 6 mo post-BMT Last hemoglobin, days post-BMT
HbA HbS HbA HbS HbF
Haploidentical
    1 NA NA 52.4 0 < 1.4 100 1.4 0.4 184.6 130.2 10.80 11.40 13.6 (1087)
    3 57.9 38.4 55.1 40.4 100 9.8 0.5 425.1 79.2 7.1 13.90 14.8 (783)
    6 NA NA 94.8 < 5.0 1 87 1.6 0.2 234.6 45.8 10.2 11.50 11 (722)
    7 57.9 38.9 56.5 39.2 < 1.4 100 0.5 0.2 54.2 40.3 8.6 11.10 9.6 (385)
    9 55.7 39.6 23.6 60.8 11 11 4.8 2.1 357 232.6 9.5 6.80 6.2 (365)
    10 57 38.2 56.1 38.7 100 0.5 0.2 31.3 68.2 8.9 9.40 11.1 (365)
    16 100 0 100 100 2.2 0.2 229.4 31.8 10.3 13.00 13 (189)
    17 55.6 39.7 54.2 40.8 100 2.4 0.4 332.6 113.7 10.6 12.00 12 (178)
        Median 1.9 0.3 232 79.2 9.85 11.45 11.55
HLA-matched
    4 55.4 40.7 55 40.3 87 7.4 0.6 372.9 55.7 8.8 13.70 15 (731)
    11 68.8 33.1 63.2 31.4 89 2.3 0.2 169.9 45.7 10.2 11.50 11.5 (187)
    13 55.4 40.3 60.6 28 8.5 52 4.9 1.9 210.4 119.6 10.1 8.50 9.5 (304)
        Median 4.9 0.6 210.4 55.7 10.10 11.50 11.5

Comparison of hemoglobin variants A, S, and fetal between donors and recipients at the 6-mo posttransplant visit, contrasting it with peripheral blood chimerism in peripheral blood (unsorted) at the same time. Patients 5 and 13 received packed red blood cells within 30 days of this testing. Also comparison of absolute reticulocyte numbers (upper limit of normal is 87 × 103/mm3), hemoglobin (lower limit of normal is 12 g/dL), and total bilirubin (upper limit of normal is 1.2 mg/dL).

*

Patient 1 has 40.9% hemoglobin C 6 mo post-BMT.

Reticulocyte value obtained 76 days post-BMT.

Pretransplant hemoglobin values reflect transfusions received.

HHS Vulnerability Disclosure