Fig. 3. Urinary excretion of Na⁺ and K⁺ in WNK3 knockout mice.

There were no significant differences in urine volume (A), urinary Na⁺ excretion (B) or K⁺ excretion (C) between WNK3 knockout mice (squares, n = 8) and their wild-type littermates (circles, n = 8). On day 0, mice were switched from low-salt diet (0.01% NaCl) to high-salt diet (4.0% NaCl). Before switching diet, mice were fed low-salt diet for 1 week. n.s. not significant.