Table 2.
Baseline clinical characteristics of the patients and NC in the study
| Variable | NC (n = 37) | AD (n = 61) | LBD (n = 16) | p value (overall, n = 114) | p value (AD vs. LBD, n = 77) |
|---|---|---|---|---|---|
| Age, years | 70.6 (6.2) | 75.2 (7.7) | 75.5 (5.2) | 0.005a | 0.89 |
| Education, years | 10.0 (2.3) | 9.3 (2.5) | 8.5 (1.9) | 0.042a | 0.176 |
| Sex, male:female | 13:24 | 14:47 | 13:3 | <0.001b | <0.001b |
| MMSE | 28.8 (1.0) | 23.9 (2.3) | 24.3 (2.5) | <0.001a | 0.314 |
| CVLT-II1 | – | 19.2 (7.0) | 23.2 (9.3) | – | 0.198 |
| Verbal fluency2 | – | 13.0 (6.2) | 11.5 (4.2) | – | 0.409 |
| Apoɛ4, yes:no | 11:25 | 27:14 | 4:6 | 0.007c | 0.133d |
| HIS | – | 2.9 (2.1) | 3.6 (1.9) | – | 0.109 |
| CDR-SOB | – | 4.4 (2.0) | 4.8 (2.6) | – | 0.578 |
| CIRS3 | – | 0.11 (0.32) | 0.42 (0.67) | – | 0.045 |
Values in parentheses are standard deviations. Mann-Whitney U test was used, except if otherwise indicated. APOE ɛ4 yes means subject has at least one APOE ɛ4 allele.
1
The CVLT-II score is available for 61 AD patients and 14 LBD patients.
2
The verbal fluency score is available for 60 AD patients and 16 LBD patients.
3
The CIRS score is available for 61 AD patients and 12 LBD patients.
a
Kruskal-Wallis H test.
b
Pearson's χ2 = 18.9;
c
Pearson's χ2 = 9.9;
d
Pearson's χ2 = 2.5.