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. 2012 Nov 9;2(1):481–495. doi: 10.1159/000343480
MR imaging parameters TR = Repetition time; TE = echo time; TI = inversion time; FA = flip angle; ST = slice thickness; NEX = number of excitations; FOV = field of view, and VS = voxel size.
3D T1-weighted sequence
Stavanger University Hospital FFE, TR/TE/FA = 10.0 ms/4.6 ms/30°, ST = 2 mm with 1 mm spacing between slices, NEX = 2, Image Matrix = 256 × 256, FOV 26 cm, VS = 1.0156 × 1.0156 × 1 mm.
Haugesund Hospital FFE, TR/TE/FA 20.0 ms/4.6 ms, 30°, ST = 1 mm with 1 mm spacing, NEX = 1, Image Matrix = 256 × 256, FOV 26 cm, VS = 0.5078 × 0.5078 × 1 mm.
Haraldsplass Deaconess Hospital, Bergen FSPGR IR prepped, TR/TE/TI/FA 8.3 ms/3.2 ms/500 ms/7°, ST = 1 mm with 1 mm spacing, NEX = 1, Image Matrix = 256 × 256, FOV 25.6 cm, VS = 1 × 1 × 1 mm.
Bergen (ParkWest) TR/TE/TI/FA 2,130.0/3.9 msec/1,100 msec/15°, ST = 1 mm with 1 mm spacing, NEX 1, Image Matrix 256 × 256, FOV 25 cm, VS = 0.9766 × 0.9766 × 1 mm.
Arendal FFE, TR/TE/FA 25/6.9 msec/30°, ST = 2 mm with 2 mm spacing, NEX 1, Image Matrix 256 × 256, FOV 26.0 cm, VS = 1.0156 × 1.0156 × 2.
FLAIR sequence
Stavanger University Hospital TR/TE/TI/FA 6,000 ms/100 ms/2,000 ms/90°, ST = 4 mm with 5 mm spacing, NEX = 2, Image Matrix = 256 × 256, FOV 23.0 cm, VS = 0.8984 × 0.8984 × 4 mm.
Haugesund Hospital TR/TE/TI/FA 6,000 ms/110 ms/2,000 ms/90°, ST = 4 mm with 5 mm spacing, NEX = 2, FOV 24.0 cm, Image Matrix = 512 × 512, VS = 0.4688 × 0.4688 × 4 mm.
Haraldsplass deaconess hospital, Bergen TR/TE/TI/FA = 7,927 ms/105 ms/1,981 ms/90°, ST = 4 mm with 5 mm spacing, NEX = 1, Image Matrix 256 × 256, FOV 25.0 cm, VS = 0.9766 × 0.9766 × 4 mm.
Bergen TR/TE/TI/FA 8,400/103/2,500/150, ST = 4 mm with 4.4 mm spacing, NEX 2, Image Matrix 256 × 204, VS = 0.9766 × 0.9766 × 4 mm.
Arendal TR/TE/TI/FA 6,000/100/1,900/90°, ST = 4 mm with 5 mm spacing, NEX 2, Image Matrix 256 × 256, FOV 23.0 cm og VS = 0.8984 × 0.8984 × 4 mm.
Scanner reliability analysis The human phantoms were scanned twice, 1 h apart, in all centers to analyze scanner reliability between centers. Scanning was organized with two separate sessions, 1 h apart, on the same day. From these scans, the total brain white matter was segmented from the T1 image and the volume calculated for the two MRI acquisitions at all four centers using FreeSurfer (http://surfer.nmr.mgh.harvard.edu/).