Table 4.
Multivariate relative risk of ovarian cancer in relation to the combination of BMI at baseline and BMI at age 18 years in all women and in subgroups of women defined by selected variables*
| All women | ||
| BMI (kg/m2) | RR (95% CI) | |
| At baseline | At age 18 years | |
| <25.0 | <25.0 | 1.0 (ref.) |
| <25.0 | ≥25.0 | 1.26 (0.52–1.32) |
| ≥25.0 | <25.0 | 1.01 (0.78–1.30) |
| ≥25.0 | ≥25.0 | 1.41 (0.89–2.32) |
| Women who never used menopausal hormones | ||
| BMI (kg/m2) | RR (95% CI) | |
| At baseline | At age 18 years | |
| <25.0 | <25.0 | 1.0 (ref.) |
| <25.0 | ≥25.0 | 1.56 (0.37–6.49) |
| ≥25.0 | <25.0 | 1.46 (0.95–2.24) |
| ≥25.0 | ≥25.0 | 2.99 (1.69–5.29) |
| Women with hysterectomy | ||
| BMI (kg/m2) | RR (95% CI) | |
| At baseline | At age 18 years | |
| <25.0 | <25.0 | 1.0 (ref.) |
| <25.0 | ≥25.0 | - |
| ≥25.0 | <25.0 | 1.05 (0.64–1.73) |
| ≥25.0 | ≥25.0 | 2.04 (0.93–4.49) |
| Women who never used postmenopausal hormones with hysterectomy | ||
| BMI (kg/m2) | RR (95% CI) | |
| At baseline | At age 18 years | |
| <25.0 | <25.0 | 1.0 (ref.) |
| <25.0 | ≥25.0 | - |
| ≥25.0 | <25.0 | 2.48 (0.54–1.51) |
| ≥25.0 | ≥25.0 | 9.41 (1.82–8.55) |
| Women with no family history of ovarian cancer | ||
| BMI (kg/m2) | RR (95% CI) | |
| At baseline | At age 18 years | |
| <25.0 | <25.0 | 1.0 (ref.) |
| <25.0 | ≥25.0 | 1.19 (0.44–3.24) |
| ≥25.0 | <25.0 | 1.11 (0.85–1.47) |
| ≥25.0 | ≥25.0 | 1.68 (1.05–2.68) |
The reference group are the women who jointly fell into the categories of BMI at baseline<25.0 kg/m2 and BMI<25.0 kg/m2 at age 18 years. The multivariate model included the covariates listed in Table 2 footnote.