Table 3.
Spearman correlations between obesity measures and insulin resistance measures in obese adolescents
| n | Fasting insulin | CIRgp | CISI | IGFBP-1 | |
|---|---|---|---|---|---|
| BMI z-score | 92 | 0.29 (P = 0.006) | 0.24 (P = 0.022) | –0.31 (P = 0.003) | –0.39 (P < 0.001) |
| Waist (UMB) | 90 | 0.18 (P = 0.09) | 0.09 (P > 0.40) | –0.17 (P > 0.10) | –0.27 (P = 0.01) |
| Waist (NHANES) | 63 | 0.29 (P = 0.020) | 0.17 (P > 0.10) | –0.27 (P = 0.03) | –0.47 (P < 0.001) |
| DXA lean mass | 91 | 0.25 (P = 0.02) | 0.21 (P = 0.047) | –0.24 (P = 0.02) | –0.39 (P < 0.001) |
| DXA fat mass | 91 | 0.10 (P > 0.30) | 0.13 (P > 0.20) | –0.06 (P > 0.50) | –0.22 (P = 0.03) |
| CT-IP fat area | 87 | 0.35 (P = 0.001) | 0.01 (P > 0.90) | –0.34 (P = 0.002) | –0.44 (P < 0.001) |
| CT-SQ fat area | 87 | 0.14 (P > 0.10) | 0.11 (P > 0.30) | –0.13 (P > 0.20) | –0.23 (P = 0.03) |
| IGFBP-1 | 92 | –0.47 (P < 0.001) | –0.34 (P = 0.001) | 0.51 (P < 0.001) | – |
CIRgp, corrected insulin release at the glucose peak; CISI, composite insulin sensitivity index; CT-IP, intraperitoneal fat measured by computed tomography; CT-SQ, subcutaneous fat measured by computed tomography; DXA, dual-energy X-ray absorptiometry; IGFBP-1, insulin-like growth factor-binding protein-1; NHANES, National Health and Nutrition Examination Survey; UMB, umbilicus.