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. Author manuscript; available in PMC: 2012 Nov 27.
Published in final edited form as: Vaccine. 2011 Jul 29;29(43):7326–7334. doi: 10.1016/j.vaccine.2011.07.071

Fig. 6.

Fig. 6

Measurement of virus specific neutralizing antibody titer in mice sera immunized with monovalent vaccine formulated using Pichia pastoris expressed HPV16 VLPs or HPV18 VLPs. Geometric mean titer (GMT) of neutralizing serum antibody of mice immunized with various antigenic payloads of HPV16 or 18 VLP produced in Pichia pastoris. Neutralization titer is reported as maximum sera dilution resulting in >50% inhibition of SEAP activity. Group I of HPV16 is 2 μg and HPV18 is 1 μg; Group II of HPV16 is 10 μg and HPV18 is 3 μg; Group III of HPV16 indicate 20 μg and HPV18 is 5 μg – 16pla: HPV16 Placebo group; 18pla: HPV18 placebo group.