Figure 2.

Age-related changes in recognition memory and brain activations associated with successful retrieval. a, HIT rate improved significantly with age (individual values in closed circles; regression with age, solid line), and CR accuracy did not change significantly with age (individual values in open circles; regression with age, dashed line). b, Activations associated with retrieval success (rendered on a standard brain's left lateral view) increased with age in left parietal and frontal regions as indicated by regression analysis using age as a continuous variable across participants. Voxel-level threshold, p < 0.001; cluster extent, >50 contiguous voxels. c, For visual presentation, parietal activations depicted in b were overlaid on a surface based representation of the MNI canonical brain using the SPM SurfRend Toolbox (http://spmsurfrend.sourceforge.net). A t value scale is presented at bottom right. d, Time courses for the HIT and CR conditions in left superior parietal cortex were extracted for each participant and averaged across participants in three age groups corresponding to children (left; n = 27; 8–12 years old), adolescents (middle; n = 24; 13–17 years old), and adults (right; n = 18; 18–21 years old). HIT, Closed circles, solid line; CR, open circles, dashed line.