Figure 2. Estrogen administration increases bone mass in long bones independent of FSH.

A) Representative cross-sectional µCT scans of the femoral diaphyses of untreated (-E2) or treated (+E2) Fshb^+/+ and Fshb^−/− mice. B) Von Kossa/van Gieson-staining of non-decalcified tibia sections and quantification of the BV/TV and cortical thickness (C.Th.). All data represent mean ± SD from at least 5 mice per group. *p<0.05 versus untreated control of each genotype.