Table 3. Correlation between fascin-1, ezrin and paxillin immunostaining rank and clinicopathological characteristics.

		Mean rank
Clinicopathological characteristics	No.	Fascin-1	P	Ezrin	P	Paxillin	P
Median age
<59 years	107	102.86	0.113	93.86	<0.001	104.70	0.277
≥59 years	109	114.03		122.87		112.23
Gender
Female	23	10967	0.908	102.04	0.547	106.65	0.854
Male	193	108.36		109.27		108.72
Primary sites
Glottic	116	93.53	<0.001 *	94.68	0.248*	105.60	0.320*
Supraglottic	96	125.09		100.33		110.60
Subglottic	4	144.50		131.00		142.00
Histologic differentiation
Well	84	82.04	<0.001 *	77.30	<0.001 *	81.35	<0.001 *
Moderate	89	123.57		108.06		127.42
Poor	43	129.01		119.98		122.40
Primary tumor
T1+ T2	126	100.50	0.007	102.29	0.047	104.40	0.161
T3+ T4	90	119.70		117.20		114.23
Cervical lymph node metastasis
N0	161	101.96	0.002	101.78	0.002	102.89	0.006
N+	55	127.65		128.16		124.91
Distant metastasis
M0	211	107.65	0.116	107.93	0.318	107.71	0.136
M1	5	144.50		135.50		142.00
Clinical stage
I+ II	104	97.25	0.002	99.69	0.022	99.25	0.010
III+ IV	112	118.95		116.68		117.09
Smoking status
No	84	98.11	0.019	99.63	0.056	101.46	0.104
Yes	132	115.11		114.15		112.98

^*By Kruskal-Wallis H(K) test; others by Mann-Whitney U test.