Table 1.
Baseline characteristics between CKDcohort and non-CKD cohort
|
non-CKD N = 74098 |
CKD N = 37049 |
|
||
---|---|---|---|---|---|
n | % | n | % | P value* | |
Sex |
|
|
|
|
1.00 |
Women |
33948 |
45.8 |
16974 |
45.8 |
|
Men |
40150 |
54.2 |
20075 |
54.2 |
|
Age group (years) |
|
|
|
|
1.00 |
20–39 |
10710 |
14.5 |
5355 |
14.5 |
|
40–64 |
34742 |
46.9 |
17371 |
46.9 |
|
≥65 |
28646 |
38.7 |
14323 |
38.7 |
|
Mean (SD) (years) |
57.5 |
(15.8) |
58.3 |
(16.1) |
<0.0001 |
Co-morbidities |
|
|
|
|
|
Hypertension |
23702 |
32.0 |
21731 |
58.7 |
<0.0001* |
Diabetes mellitus |
6367 |
8.59 |
11517 |
31.1 |
<0.0001* |
Ischemic heart disease |
12896 |
17.4 |
12056 |
32.5 |
<0.0001* |
Hyperlipidemia |
7350 |
9.92 |
9762 |
26.4 |
<0.0001* |
Tobacco use disorder |
138 |
0.19 |
135 |
0.36 |
<0.0001* |
Alcoholism |
294 |
0.40 |
335 |
0.90 |
<0.0001* |
Obesity |
398 |
0.54 |
401 |
1.08 |
<0.0001* |
Atrial fibrillation |
638 |
0.86 |
740 |
2.00 |
<0.0001* |
Parkinson's disease |
790 |
1.07 |
680 |
1.84 |
<0.0001* |
Cerebrovascular disease |
8701 |
11.7 |
7876 |
21.3 |
<0.0001* |
Major depressive disorder |
852 |
1.15 |
652 |
1.76 |
<0.0001* |
Elevated C-reactive protein |
-- |
|
-- |
|
-- |
Medication |
|
|
|
|
|
Use of benzodiazepine |
37902 |
51.2 |
25284 |
68.2 |
<0.0001* |
Use of aspirin |
6992 |
9.44 |
5822 |
15.7 |
<0.0001* |
Use of other NSAIDs |
63174 |
85.3 |
34698 |
93.7 |
<0.0001* |
Use of COX2 | 14584 | 19.7 | 10901 | 29.4 | <0.0001* |
*Chi-square test comparing patients with and without CKD.