Table 4.
Multivariate analysis of factors associated with mortality among cases of hospital-associated and community-acquired Staphylococcus aureus bacteraemia in Denmark from 1995-2008
| |
Hospital-associated SAB |
Community-acquired SAB |
||
|---|---|---|---|---|
| 30-d mortality (%) | Adjusted MRR (95% CI) | 30-d mortality (%) | Adjusted MRR (95% CI) | |
|
Overall |
2368/9412 (25.2%) |
|
1439/5074 (28.4%) |
|
|
Age, years |
|
|
|
|
| 1 > |
19/337 (5.6%) |
0.45 (0.28-0.73) |
1/58 (1.7%) |
0.13 (0.02-0.93) |
| 1-15 |
9/232 (3.9%) |
0.27 (0.14-0.53) |
1/235 (0.4%) |
0.03 (0.04-0.23) |
| 16-35 |
32/535 (6.0%) |
0.39 (0.27-0.56) |
15/405 (3.7%) |
0.25 (0.14-0.42) |
| 36-55 |
282/1733 (16.3%) |
1.0 |
152/938 (16.2%) |
1.0 |
| 56-75 |
983/3982 (24.7%) |
1.7 (1.5-1.9) |
483/1734 (27.9%) |
1.8 (1.5-2.2) |
| > 75 |
1043/2593 (40.2%) |
3.2 (2.8-3.7) |
787/1704 (46.2%) |
3.6 (3.0-4.4) |
|
Sex |
|
|
|
|
| Female |
988/3755 (26.3%) |
1.0 |
616/1927 (32.0%) |
1.0 |
| Male |
1380/5657 (24.4%) |
0.90 (0.83-0.98) |
823/3147 (26.2%) |
0.82 (0.74-0.92) |
|
CCI score |
|
|
|
|
| 0 |
527/2822 (18.7%) |
1.0 |
435/2293 (19.0%) |
1.0 |
| 1-2 |
1049/3868 (27.1%) |
1.3 (1.1-1.4) |
606/1801 (33.6%) |
1.3 (1.1-1.5) |
| > 2 |
792/2722 (29.1%) |
1.4 (1.2-1.6) |
398/980 (40.6%) |
1.6 (1.4-1.9) |
|
Alcohol-related disorders |
|
|
|
|
| No |
2113/8585 (24.6%) |
1.0 |
1251/4532 (27.6%) |
1.0 |
| Yes |
255/827 (30.8%) |
1.7(1.5-2.0) |
188/542 (34.7%) |
1.9(1.6-2.2) |
|
Year |
|
|
|
|
| 1995-1997 |
526/1893 (27.8%) |
1.0 |
262/989 (26.5%) |
1.0 |
| 1998-2000 |
502/1992 (25.2%) |
0.83 (0.74-0.94) |
365/1261 (28.9%) |
1.00 (0.85-1.17) |
| 2001-2003 |
512/2010 (25.5%) |
0.79 (0.70-0.89) |
257/893 (28.8%) |
0.89 (0.75-1.06) |
| 2004-2006 |
535/2171 (24.6%) |
0.74 (0.66-0.84) |
355/1155 (30.7%) |
0.90 (0.76-1.05) |
| 2007-2008 | 293/1346 (21.8%) | 0.65 (0.56-0.75) | 200/776 (25.8%) | 0.74 (0.61-0.89) |
SAB: Staphylococcus aureus bacteraemia; MRR: Mortality rate ratio; CI: confidence interval, CCI: Charlson comorbidity index.