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. 2012 Nov 27;7(11):e50053. doi: 10.1371/journal.pone.0050053

Figure 3. GC-box1 plays a major role in MGARP promoter activation and both GC-boxes are required for full transactivation.

Figure 3

The Luc reporters driven by the full-length MGARP promoter (−3 kb) were transfected into HEK-293T cells, as compared to various promoter truncates either missing the GC-Boxes or expressing the GC-Boxes alone, without or with co-transfection of Sp1 plasmids (10 ng) as indicated. Luc activity was examined at 72 hours post transfection. *** represents p<0.001 and #represents p>0.05 (no significant difference).