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. 2012 Nov 27;7(11):e49810. doi: 10.1371/journal.pone.0049810

Figure 1. CG32169, also known as Rbp6, is a paralogue of dMsi and an orthologue of mammalian Msi proteins.

Figure 1

(A) Genomic representation of CG32169 (Rbp6) on chromosome 3L (modified from Flybase). (B) CG32169 (Rbp6) has six transcripts. Exons encoding for RRM1 and RRM2 are coloured green and blue respectively, and coding start sites are indicated (red arrow). The region to which the RNA probe was designed is underlined. (C) Sequence alignment of CG32169 (Rbp6) isoform A with dMsi, mouse Msi-1 and Msi-2 using CLUSTALW. Single-letter amino acid codes are used. Alignments among the four proteins are highlighted by black boxes for identical amino acids, and by grey boxes for similar amino acids. The two RNA recognition motifs are noted with a green or blue line. Each RRM includes two highly conserved sequences designated RNP-1 and RNP-2.