Figure 4. Negative.
ΔS-O2 response. Representative results obtained from a patient with recurrent GB (patient number 4), showing negative ΔS-O2 response during hyperoxic challenge observed distant from the tumor area. (A) ΔS-O2 map; (B) T1WI post contrast agent injection and (C) fluid attenuation inversion recovery (FLAIR) image. (D) The mean time courses of the signal intensity change (%) during hyperoxic challenge obtained from the area with negative response (VOI is marked by red rectangle on Figure 4A).