Table 3. HRI and rCBV values calculated at the lesion and contra lateral side VOIs.

Patient No		rCBV		ΔS-O2 (%)		ΔS-CO2(%)		Vascular reactivity index1
		lesion	CLS	lesion	CLS	lesion	CLS	lesion	CLS
1	Atypical Meningioma	8.2	1.9	3.32	2.82	1.09	0.93	19%	9%
2	Glioblastoma	2.5	1.2	1.94	1.93	0.72	1.08	27%	7%
3	Glioblastoma	4.1	NA2	1.10	NA2	0.33	NA2	13%	NA2
4	Recurrent Glioblastoma	2.6	1.7	1.00	2.02	0.19	0.60	12%	7%
5	Recurrent Glioblastoma	3.7	1.9	1.05	1.93	0.38	0.87	15%	10%
6	Recurrent Glioblastoma	NA3	NA3	1.07	1.50	0.63	0.80	2%	12%
7	Recurrent Glioblastoma	NA3	NA3	0.55	1.48	0.09	0.15	13%	43%

ΔS = percent signal intensity changes; rCBV = relative cerebral blood volume; CLS = contralateral side.

¹Vascular reactivity index, number of voxels (in percentages) above the defined VRM threshold.

²Lesion crosses brain midline, thus contralateral side VOI could not be defined.

³DSC perfusion was not performed.