Table 1.
Proteins | Disordered residues compared to wild type | Helices affected |
---|---|---|
R72D | 1–15 | Helix 1 |
D122R | 5 –15, 100–140 | Helix 1, Helix 3, Helix 4 |
L134P | 123–135 | Helix 3 |
B′-factors values are 2–4 times greater than wild type, as determined from XRD of protein crystals, 1.5 Å resolution 3. The N-terminal extension includes residues 1–11 and the channel residues are 110–134; helix 3 has residues 92–119 and helix 4 has residues 125–155.