Table 3.

Kinetics of formation of Fe(III)-O^a formation in variant ferritins

Sample	Fe(III)-Oa formation rate (Vib)
	(ΔAbs350 nm/sec)	Normalized
WT	0.82 ± 0.09	1.0
R72D	1.03 ± 0.05b	1.25 ± 0.06c,d
D122R	0.27 ± 0.05b,c	0.39 ± 0.07 c,d
L134P	0.15 ± 0.06b,c	0.18 ± 0.08c,d

^aThe species containing Fe(III)-O unit which includes DFP, ferric oxo/hydroxo dimers, multimers and the protein-caged ferric oxide mineral.

^bInitial rates were obtained from linear fitting, first ~ 50 ms, of ΔAbs_{350 nm}.

^cSignificantly different than wild type, P<0.003.

^dSignificantly different than R72D, P<0.003.