TABLE 2.
Logistic regression results for both the additive and dominant adjusted models for LAMC1 SNPs adjusted for age, BMI, and vaginal parity
| SNP | Minor allele (frequency) | Dominant adjusted model
|
Additive adjusted model
|
||
|---|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | ||
| rs10911193 | T (0.11) | 1.29 (0.77–2.17) | .34 | 1.23 (0.77–1.97) | .39 |
|
| |||||
| rs1413390 | G (0.45) | 1.45 (0.92–2.29) | .11 | 1.22 (0.90–1.65) | .21 |
|
| |||||
| rs20558 | T (0.45) | 1.44 (0.91–2.26) | .12 | 1.19 (0.88–1.61) | .25 |
|
| |||||
| rs20563 | A (0.46) | 1.44 (0.92–2.28) | .11 | 1.20 (0.89–1.63) | .23 |
|
| |||||
| rs10911206 | A (0.48) | 1.37 (0.85–2.20) | .19 | 1.16 (0.85–1.57) | .35 |
|
| |||||
| rs2296291 | C (0.45) | 1.36 (0.85–2.16) | .20 | 1.14 (0.84–1.56) | .39 |
|
| |||||
| rs12041030 | G (0.11) | 1.36 (0.80–2.29) | .25 | 1.28 (0.80–2.07) | .30 |
|
| |||||
| rs12739316 | T (0.41) | 0.79 (0.51–1.23) | .30 | 0.82 (0.60–1.11) | .20 |
|
| |||||
| rs3768617 | T (0.42) | 0.83 (0.53–1.31) | .42 | 0.84 (0.61–1.16) | .29 |
|
| |||||
| rs2483675 | A (0.22) | 1.15 (0.76–1.74) | .51 | 1.17 (0.82–1.68) | .38 |
|
| |||||
| rs10911211 | T (0.40) | 0.89 (0.57–1.39) | .62 | 0.90 (0.66–1.24) | .52 |
|
| |||||
| rs41475048 | T (0.25) | 1.04 (0.69–1.56) | .86 | 1.08 (0.77–1.50) | .66 |
|
| |||||
| rs1058177 | C (0.09) | 1.01 (0.58–1.76) | .97 | 1.01 (0.58–1.76) | .97 |
|
| |||||
| rs12073936 | G (0.08) | 1.00 (0.56–1.78) | .99 | 0.96 (0.55–1.68) | .88 |
BMI, body mass index; CI, confidence interval; LAMC1, laminin gamma-1; OR, odds ratio; SNP, single-nucleotide polymorphism.