Table 4.
Variables | Odds Ratio (95% Confidence Interval) | P Value | Trend P Value |
---|---|---|---|
Age (years) | |||
<35 | Reference group | ||
35–40 | 1.06 (0.58–1.93) | 0.85 | |
>40 | 0.75 (0.40–1.38) | 0.35 | |
Race | |||
White | Reference group | ||
Black | 1.38 (0.64–2.98) | 0.41 | |
Hispanic | 0.95 (0.40–2.26) | 0.91 | |
HCV-RNA (IU/mL) | |||
<1,310,000 | Reference group | ||
1,310,001–2,740,000 | 0.66 (0.29–1.54) | 0.34 | |
2,740,001–3,940,000 | 0.67 (0.28–1.63) | 0.38 | 0.10 |
>3,940,000 | 0.44 (0.18–1.09) | 0.07 | |
HIV-viral load (copies/mL) | |||
<5000 | Reference group | ||
5000–9999 | 0.79 (0.23–2.76) | 0.71 | |
10,000–49,000 | 0.63 (0.29–1.40) | 0.26 | 0.03 |
50,000–99,999 | 0.63 (0.25–1.55) | 0.31 | |
100,000+ | 0.30 (0.11–0.84) | 0.02 | |
Intravenous drug use (in the past 6 months) | |||
No | Reference group | ||
Yes | 2.67 (0.90–7.75) | 0.07 | |
Current smoking | |||
No | Reference group | ||
Yes | 1.93 (0.83–4.49) | 0.13 | |
Antiretroviral therapy | |||
None | Reference group | ||
Monotherapy | 0.99 (0.41–2.41) | 0.99 | |
Combination therapy | 1.47 (0.75–2.89) | 0.26 | |
Current HAART use | |||
No | Reference group | ||
Yes | 4.28 (2.53–7.22) | <0.0001 | |
CD4 cell count/mm3 | |||
>500 | Reference group | ||
350–500 | 0.88 (0.39–1.98) | 0.76 | |
200–349 | 0.37 (0.16–0.86) | 0.02 | 0.08 |
<200 | 0.60 (0.25–1.43) | 0.25 | |
CD8 cell count/mm3 | |||
<500 | Reference group | ||
500–1199 | 0.66 (0.30–1.47) | 0.31 | 0.13 |
1200 or more | 1.48 (0.56–3.94) | 0.43 | |
Heroin use | |||
No | Reference group | ||
Yes | 2.33 (0.85–6.40) | 0.52 | |
Cocaine use | |||
No | Reference group | ||
Yes | 1.12 (0.52–2.44) | 0.77 | |
Methadone use | |||
No | Reference group | ||
Yes | 2.89 (0.44–18.9) | 0.27 | |
Number of sex partners | |||
None | Reference group | ||
1 | 0.71 (0.34–1.47) | 0.35 | 0.30 |
2 or more | 0.64 (0.25–1.60) | 0.34 |
All the exposures are from previous visit, except for HAART, which is from the current visit.