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. Author manuscript; available in PMC: 2013 Aug 6.
Published in final edited form as: Matrix Biol. 2012 Aug 6;31(6):360–367. doi: 10.1016/j.matbio.2012.07.003

Figure 5. Dose-dependence of FN assembly inhibition by four compounds identified from cherry pick testing.

Figure 5

AH1F cells were plated into 96-well plates and incubated with increasing doses of piperlongumine (PPLGN), ML-9, imatinib mesylate or tyrphostin. ML-7 and 1 μM FUD were included as known inhibitors of FN assembly. Wells were analyzed for fluorescence (F) and luminescence (L). Points are the averages of 3 assays, with fluorescence (F) and fluorescence/luminescence (F/L) expressed as percentages of values obtained from A488-FN incubated on cells without compounds. Error bars = SD of 3 experiments, each assay point in triplicate.