Table 1.
Inventory of biotin-dependent carboxylases in some common organisms
| Organism | Biotin-dependent carboxylase (family number) |
|---|---|
| Bacteria | |
| Escherichia coli K-12 | Multi-subunit ACC (1.1) |
| Pseudomonas aeruginosa PAO1 | Multi-subunit ACC (1.1), multi-domain YCC (1.6), MCC (2.1), GCC (2.1), two-subunit PC (3.2), multi-subunit UC (4.3) |
| Ruegeria pomeroyi DSS-3 | Multi-subunit ACC (1.1), PCC (1.5), MCC (2.1), GCC (2.1), PC (3.1) |
| Cupriavidus metallidurans CH34 | Multi-subunit ACC (1.1), multi-domain YCC (1.6, 2 copies), MCC (2.1), GCC (2.1), PC (3.1) |
| Deinococcus radiodurans R1 | Multi-subunit ACC (1.1), multi-domain YCC (1.6), PCC (1.5), MCC (2.1) |
| Streptomyces coelicolor A3(2) | Two-subunit YCC (1.4), PCC (1.5, 2 copies), MCC (2.1, 2 copies), PC (3.1) |
| Staphylococcus aureus | Multi-subunit ACC (1.1), PC (3.1), multi-subunit UC (4.3) |
| Bacillus subtilis | Multi-subunit ACC (1.1), three-subunit YCC (1.4), PC (3.1) |
| Archaea | |
| Methanocauldococcus jannaschii | Two-subunit PC (3.2) |
| Metallosphaera sedula | Two subunit YCC (1.4) |
| Fungi | |
| Saccharomyces cerevisiae | Eukaryotic ACC (1.7, 2 copies), PC (3.1, 2 copies), UC (4.1) |
| Kluyveromyces lactis | Eukaryotic ACC (1.7), PC (3.1), UC (4.1) |
| Schizosaccharomyces pombe | Eukaryotic ACC (1.7), PC (3.1) |
| Animals | |
| Xenopus laevis | Eukaryotic ACC (1.7), PCC (1.5), MCC (2.1), PC (3.1) |
| Danio rerio | Eukaryotic ACC (1.7), PCC (1.5), MCC (2.1), PC (3.1) |
| Mus musculus | Eukaryotic ACC (1.7, 2 copies), PCC (1.5), MCC (2.1), PC (3.1) |
| Homo sapiens | Eukaryotic ACC (1.7, 2 copies), PCC (1.5), MCC (2.1), PC (3.1) |